Atropine (Ophthalmic)

Generic name: atropine, homatropine, and scopolamine (Ophthalmic route)

Commonly used brand name(s)

In the U.S.

  • AK-Dilate
  • AK-Pentolate
  • Altafrin
  • Atropine Care
  • Cyclogyl
  • Cyclomydril
  • Eye Cool
  • Homatropaire
  • Isopto Atropine
  • Isopto Homatropine
  • Isopto Hyoscine
  • Mydfrin
  • Mydral
  • Mydriacyl
  • Neofrin
  • Neo-Synephrine
  • Omidria
  • Paremyd

In Canada

  • Ak-Dilate
  • Ak-Pentolate
  • Atropine
  • Atropine-Ak
  • Atropine Eye Ointment
  • Atropine Ointment
  • Atropisol
  • Minims Phenylephrine Hydrochloride

Available Dosage Forms:

  • Solution
  • Ointment

Uses for Atropine

Ophthalmic atropine, homatropine, and scopolamine are used to dilate (enlarge) the pupil of the eye. They are used before eye examinations, before and after eye surgery, and to treat certain eye conditions, such as uveitis or posterior synechiae.

These medicines are available only with your doctor's prescription.

Before using Atropine

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Infants and young children and children with blond hair or blue eyes may be especially sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the chance of side effects during treatment . Children should use a lower strength of this medicine.

Geriatric

Elderly people are especially sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the chance of side effects during treatment.

Pregnancy

Studies on effects in pregnancy have not been done in either humans or animals. However, these medicines may be absorbed into the body.

Breastfeeding

These medicines may be absorbed into the body. Atropine passes into the breast milk in very small amounts and may cause side effects, such as fast pulse, fever, or dry skin, in babies of nursing mothers using ophthalmic atropine. It is not known whether homatropine or scopolamine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are using one of these medicines and who wish to breast-feed should discuss this with their doctor.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Aceclofenac
  • Acemetacin
  • Amtolmetin Guacil
  • Aspirin
  • Bromfenac
  • Bufexamac
  • Celecoxib
  • Choline Salicylate
  • Clonixin
  • Clorgyline
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dihydroergotamine
  • Dipyrone
  • Droxicam
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Ibuprofen
  • Indomethacin
  • Iproniazid
  • Isocarboxazid
  • Ketoprofen
  • Linezolid
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Morniflumate
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Nialamide
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Pentoxifylline
  • Phenelzine
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Probenecid
  • Procarbazine
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Rasagiline
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Selegiline
  • Sodium Salicylate
  • Sulfasalazine
  • Sulindac
  • Tenoxicam
  • Tiaprofenic Acid
  • Tolfenamic Acid
  • Tolmetin
  • Tranylcypromine
  • Valdecoxib

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Abciximab
  • Acenocoumarol
  • Amifampridine
  • Amiloride
  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Anagrelide
  • Apixaban
  • Ardeparin
  • Argatroban
  • Bemiparin
  • Bendroflumethiazide
  • Benzthiazide
  • Betamethasone
  • Betrixaban
  • Bivalirudin
  • Budesonide
  • Bumetanide
  • Bupropion
  • Cangrelor
  • Certoparin
  • Chlorothiazide
  • Chlorthalidone
  • Cilostazol
  • Citalopram
  • Clomipramine
  • Clopamide
  • Clopidogrel
  • Clozapine
  • Cortisone
  • Cyclopenthiazide
  • Cyclosporine
  • Dabigatran Etexilate
  • Dalteparin
  • Danaparoid
  • Deflazacort
  • Desipramine
  • Desirudin
  • Desmopressin
  • Desvenlafaxine
  • Dexamethasone
  • Diazoxide
  • Dibenzepin
  • Digoxin
  • Dipyridamole
  • Donepezil
  • Dothiepin
  • Doxepin
  • Duloxetine
  • Edoxaban
  • Enoxaparin
  • Eplerenone
  • Epoprostenol
  • Eptifibatide
  • Erdafitinib
  • Ergonovine
  • Escitalopram
  • Ethacrynic Acid
  • Feverfew
  • Fluocortolone
  • Fluoxetine
  • Fluvoxamine
  • Fondaparinux
  • Furazolidone
  • Furosemide
  • Ginkgo
  • Glycopyrrolate
  • Glycopyrronium Tosylate
  • Gossypol
  • Heparin
  • Hydrochlorothiazide
  • Hydrocortisone
  • Hydroflumethiazide
  • Iloprost
  • Imipramine
  • Indapamide
  • Inotersen
  • Iobenguane I 123
  • Iobenguane I 131
  • Lepirudin
  • Levomilnacipran
  • Lithium
  • Lofepramine
  • Meadowsweet
  • Melitracen
  • Methacholine
  • Methotrexate
  • Methyclothiazide
  • Methylergonovine
  • Methylprednisolone
  • Metolazone
  • Midodrine
  • Milnacipran
  • Nadroparin
  • Nefazodone
  • Nortriptyline
  • Opipramol
  • Paramethasone
  • Pargyline
  • Parnaparin
  • Paroxetine
  • Pemetrexed
  • Pentosan Polysulfate Sodium
  • Phenindione
  • Phenprocoumon
  • Polythiazide
  • Prasugrel
  • Prednisolone
  • Prednisone
  • Protein C
  • Protriptyline
  • Quetiapine
  • Reboxetine
  • Revefenacin
  • Reviparin
  • Rivaroxaban
  • Scopolamine
  • Secretin Human
  • Sertraline
  • Sibutramine
  • Spironolactone
  • Tacrolimus
  • Tenofovir Disoproxil Fumarate
  • Tianeptine
  • Ticagrelor
  • Ticlopidine
  • Tinzaparin
  • Tiotropium
  • Tirofiban
  • Torsemide
  • Trazodone
  • Treprostinil
  • Triamterene
  • Trichlormethiazide
  • Trimipramine
  • Venlafaxine
  • Vilazodone
  • Vorapaxar
  • Vortioxetine
  • Warfarin
  • Xipamide