Generic name: smallpox monkeypox vaccine, live non-replicating (SMAWL-pox MUN-kee-pox vak-SEEN, lyve non - REP-li-kay-ting) (Subcutaneous route)
Commonly used brand name(s)
In the U.S.
Uses for Jynneos
Smallpox monkeypox vaccine, live non-replicating, is an active immunizing agent used to prevent smallpox and monkeypox infection in adults who may be at high risk to have this disease. It works by causing your immune system to produce its own protection (antibodies) against the virus.
This vaccine is to be given only by or under the supervision of your doctor or other authorized health care professional.
Before using Jynneos
In deciding to use a vaccine, the risks of taking the vaccine must be weighed against the good it will do. This is a decision you and your doctor will make. For this vaccine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of smallpox monkeypox vaccine, live non-replicating, in the pediatric population. Safety and efficacy have not been established.
Appropriate studies have not been performed on the relationship of age to the effects of smallpox monkeypox vaccine, live non-replicating in the elderly 65 years of age and older. Safety and efficacy have not been established.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this vaccine. Make sure you tell your doctor if you have any other medical problems, especially:
- Cancer or
- HIV infection or
- Weak immune system—Should not be given in patients with these conditions.
Proper use of Jynneos
A nurse or other trained health professional will give you this vaccine. It is given as a shot under your skin (usually the upper arm).
This vaccine requires 2 doses that are given 4 weeks apart. If you miss the second shot, call your doctor to make another appointment as soon as possible.
Precautions while using Jynneos
It is very important that you receive the second dose of the vaccine series at the right times and that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
This vaccine may cause a serious allergic reaction, including anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after you receive the vaccine.
You should not receive this vaccine if you are using medicines that weaken your immune system, such as steroids, radiation, or cancer medicines.
This vaccine may not protect everyone who receives it.
Jynneos side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Incidence not known
- difficulty with swallowing
- fast heartbeat
- hives, itching, rash
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- tightness in the chest
- troubled breathing
- unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- muscle pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.